Phytochemicals: Extraction and Preliminary Investigation of Bioactive Compounds from Rumex Vesicarius and Terminalia Catappa PlantAuthor : Anandika Suryavanshi, Anand Murari Saxena, Payal Mago and Manisha Khatri
Volume 8 No.2 April-June 2019 pp 94-97
The present study was carried out for the determination of bioactive compounds from different extracts of Terminalia catappa and Rumex vesicarius. The plants are mines of several bioactive compounds also called as phytochemical compounds. These bioactive compounds are responsible for imparting such a potential medicinal property in the plants. The medicinal plant contains various types of bioactive compounds including phenols, alkaloids, terpenoids, tannins, glycosides, flavonoids etc. These bioactive compounds take part in various metabolic pathways and impart their effect. Terminalia catappa and Rumex vesicarius are such medicinal plants which are being used for medicinal purposes for long time. Both of them are rich source of potential bioactive compounds and hence carry out several biological activities effective for the treatment of various diseases. Hence the study focuses on determining the types of bioactive compounds they acquire. For this the leaves of T. catappa and dry stems of R. vesicarius were used for the extraction using different solvents with soxhlet method. The extract of different solvents was analyzed for the phytochemical test. The results obtained revealed that the type of solvents is crucial in determining the type of bioactive compounds to be present in extract. The results showed that ethanol and methanol are good solvent choice for extraction for these two plants. The results concludes that the presence of such potential and effective bioactive compounds in their extract makes them important medicinal plants and are hence employed for several researches and also used for treatment of various kinds of diseases.
Terminalia Catappa, Rumex Vesicarius, Phytochemical Compounds, Medicinal Properties
 S.M. Ahmed, “Anti-diabetic activity of Terminalia catappa Linn. leaf extracts in alloxan-induced diabetic rats”, Iranian J Pharmacol. Ther., Vol. 4, pp. 36–39, 2005.
 T. Behl and A. Kotwani, “Proposed mechanisms of Terminalia catappa in hyperglycaemia and associated diabetic complications”. Journal of Pharmacy and Pharmacology, Vol. 69, pp. 123–134, 2017.
 J.Y. Chung, C. Huang, X. Meng, Z. Dong, and C.S. Yang, “Inhibition of activator protein1 activity and cell growth by purified green tea and black tea polyphenols in H-ras-transformed cells: structure-activity relationship and mechanisms involved”, Cancer Research. Vol. 59, pp. 4610–4617, 1999.
 S.A. El-Hawary, N. M. Sokkar, Z.Y. Ali, and M. M. Yehia, “A Profile of Bioactive Compounds of Rumex vesicarius L.”, Journal of Food Science, Vol. 76, No. 8, pp. 1195-1202, 2011.
 M.C. Gordon, and J.N. David, “Natural product drug discovery in the next millennium”, Pharm Biol., Vol. 39, pp. 8-17, 2001.
 E.A. Hayouni, M. Abedrabba, M. Bouix, and M. Hamdi, “The effects of solvents and extraction method on the phenolic contents and biological activities in vitri of Tunisian Quercus coccifera L. and Juniperus phoenicea L. fruit extracts”, Food Chem., Vol. 105, pp. 1126-1134, 2007.
 M.M. Imran, M.M. Raja, J. Abdul Basith, and A. Asarudeen, “Determination of total phenol, flavonoid and antioxidant activity of edible mushrooms Pleurotus florida and Pleurotus eous”, Int Food Res J , Vol. 18, No. 2, pp. 574–577, 2011.
 S.E. Laouini, and M.R Ouahrani., Phytochemical screening, in vitro Antioxidant and Antibacterial activity of Rumex vesicarius L. extract, St. Cerc. St. CICBIA, Vol. 18, No. 4, pp. 367-376, 2017.
 H.A.M Mostafa, A.A. EL-Bakry, and Eman, A. Alam, “Evaluation of antibacterial and antioxidant activities of different plant parts of Rumex vesicarius L. (Polygonaceae)” International Journal of Pharmacy and Pharmaceutical Sciences, Vol. 3, No.2, pp. 109-118, 2011.
 P. Naitik, “Effect of Terminalia catappa on lipid profile in transplanted fibrosarcoma in rats”, Indian J Pharmacol., Vol. 44, pp. 390–392, 2012.
 J.F. Navarro-Gonzalez, and C. Mora-Fernandez, “The role of inflammatory cytokines in diabetic nephropathy”. J Am Soc Nephrol, Vol. 19, pp. 433–442, 2008.
 A.M. Neyrinck, “Polyphenol-rich extract of pomegranate peel alleviates tissue inflammation and hyper cholesterollaemia in high-fat diet-induced obese mice: potential implication of the gut microbiota”, Br. J. Nutr., Vol. 109, pp. 802–809, 2013.
 P. Prasad and N. Ramakrishnan, “Antioxidant assay of Rumex vesicarius L.”, International Journal of Current Research, Vol. 3, No. 11, pp. 074-076, 2012.
 N.S Reddy, K. Ramanjaneyulu, V. Sabbani and V. Choday, “In Vitro and in Vivo Antidiabetic Activity of Rumex Vesicarius Leaves Extract in Streptozotocin Induced Diabetic Albino Wister Rats”, Journal of Diabetes and Metabolism, Vol. 8, No. 6, pp. 745-749, 2017.
 X.H. Tang, L. Gao, Y.M. Fan, L. Z. Xu, X. N. Zhao, and Q. Xu, Mechanism of hepato-protection of Terminalia catappa L. extract on D-galactosamine-induced liver damage. American J. Chin. Med, Vol. 2, pp. 509-519, 2004.
 M.J. Yusuf, M.N. Begum, Hoque, and J.U. Chowdhury. Medicinal plants of Bangladesh, BCSIR Chittagong 749, 2009.