• About
  • Facebook
  • Twitter
  • RSS
(As ISO 9001:2015 Certified Publications)
    • Quick Search
    • Advanced Search
  • Home
  • Editorial Policy
  • Author Guidelines
  • Submission
  • Copyright Form
  • Career
  • Contact us
  • Subscription

Back to Journal

Home»Articles»Chemical Synthesis of Cobalt Nanoparticles and Determination of its Minimal Inhibitory Concentrations and Minimal Bactericidal Concentrations against S. aureus and E. coli

JournalCover

Asian Journal of Science and Applied Technology (AJSAT)

Editor Dr. Balaji Ramachandran
Print ISSN : 2249 - 0698
Frequency : Half-yearly

Chemical Synthesis of Cobalt Nanoparticles and Determination of its Minimal Inhibitory Concentrations and Minimal Bactericidal Concentrations against S. aureus and E. coli

Author : Vijayta Gupta, Monika Bhardbaj, Annuradha Gupta, Pawan K Verma and Vinay Kant
Volume 9 No.1 January-June 2020 pp 14-17

Abstract

The indiscriminate usage of antibiotics in the past few years is one of the main reasons behind increased incidences of antimicrobial resistance. The development of potent antibacterial agents to combat this problem is the need of present era. In view of this, in present study, cobalt (Co) nanoparticles were chemically synthesized by standard method. The synthesized Co nanoparticles were tested against the S. aureus and E. coli bacterial strains, and the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations (MBC) values of Co nanoparticles were determined against these bacterial strains on the day of Co nanoparticles synthesis and after their storage for 30 and 60 days. The Co nanoparticles showed antibacterial actions against S. aureus and E. coli bacterial strains. The MIC values of fresh chemically synthesized Co nanoparticles in this study for S. aureus and E. coli were 140.0 μg/ml and 100.0 μg/ml, respectively. The MBC values of these nanoparticles for S. aureus and E. coli were 260.0 μg/ml and 220.0 μg/ml, respectively. The MIC and MBC values of Co nanoparticles increased on storage of its suspensions for 30 as well as 60 days. It might be considered as potent antibacterial candidate in future after some additional investigations.

Keywords

Cobalt nanoparticles, MIC, MBC, S. aureus, E. coli

Full Text:

References

  1. K. Henderson, “Managing methicillin-resistant staphylococci: a paradigm for preventing no socomial transmission of resistant organisms”, American Journal of Infection Control, Vol. 34, pp. S46–S54, S64–S73, 2006.
  2. Sugden, R. Kelly, and S. Davies, “Combatting antimicrobial resistance globally”, Nature Microbiology, Vol. 1, pp. 16187, 2016.
  3. O’Neill, “Antimicrobial Resistance: Tackling a Crisis for the Health and Wealth of Nations”, Review on Antimicrobial Resistance, 2014; https://amrreview.org/
  4. S. Siddiqi, A. Rahman, Tajuddin, and A. Husen, “Properties of Zinc Oxide Nanoparticles and Their Activity against Microbes”, Nanoscale Research Letters, Vol. 13, pp. 2-13, 2018.
  5. Peterson, and P. Kaur, “Antibiotic Resistance Mechanisms in Bacteria: Relationships between Resistance Determinants of Antibiotic Producers, Environmental Bacteria, and Clinical Pathogens”, Frontiers in Microbiology, Vol. 9, pp. 2-21, 2018.
  6. K. Ghosh, M. Mitra, A. Fathima, H. Yadav, A. R. Choudhury, B. U. Nair, and R. Ghosh, “Antibacterial and catecholase activities of Co (III) and Ni (II) Schiff base complexes”, Polyhedron, Vol. 107, pp. 1, 2016.
  7. D. Mjos, and C. Orvig, “Metallodrugs in medicinal inorganic chemistry”, Chemical Reviews, Vol. 114, No8, pp. 4540-4563, 2014.
  8. E. McNeil, “Nanotechnology for the biologist”, Journal of Leukocyte Biology, Vol. 78, pp. 585–594, 2005.
  9. Lanone, and J. Boczkowski, “Biomedical applications and potential health risks of nanomaterials: molecular mechanisms”, Current Molecular Medicine, Vol. 6, pp. 651–663, 2006.
  10. A. Groneberg, M. Giersig, T. Welte, and U. Pison, Nanoparticle-based diagnosis and therapy. Current Drug Targets, Vol. 7, pp. 643–648, 2006.
  11. Zhang, T. Lan, J. Wang, L. Wei, Z. Yang, and Y. Zhang, “Template-free Synthesis of One-dimensional Cobalt Nanostructures by Hydrazine Reduction Route”, Nanoscale Research Letters, Vol. 6, pp. 58, 2011.
  12. Gupta, V. Kant, A. K. Sharma, and M. Sharma, “Comparative assessment of antibacterial efficacy for cobalt nanoparticles, bulk cobalt and standard antibiotics: A concentration dependant study”, Nanosystems Physics, Chemistry, Mathematics, Vol. 11, No.1, pp. 78–85, 2020.
  13. Hoseinzadeh, P. Makhdoumi, P. Taha, H. Hossini, J. Stelling, M. A. Kamal, and G. M. Ashraf, “A review on nano-antimicrobials: Metal nanoparticles, methods and mechanisms”, Current Drug Metabolism, Vol. 18, No.2, pp. 120-128, 2017.
  14. Azam, A. S. Ahmed, M. Oves, M. S. Khan, S. S. Habib, and A. Memic, “Antimicrobial activity of metal oxide nanoparticles against Gram-positive and Gram-negative bacteria: a comparative study”, International Journal of Nanomedicine, Vol. 7, pp.6003–6009, 2012.
  15. R. Morones, J. L. Elechiguerra, A. Camacho, K. Holt, J. B. Kouri, J. T. Ramirez, M. J. Yacaman, “The bactericidal effect of silver nanoparticles”, Nanotechnology, Vol. 16, No.10, pp. 2346–2353, 2005.
  16. Wahab, Y-S. Kim, A. Mishra, S-I. Yun, and H-S Shin, “Formation of ZnO micro-flowers prepared via solution process and their antibacterial activity”, Nanoscale Research Letters, Vol. 5, pp. 1675-1681, 2010.
  17. Ravikumar, R. Gokulakrishnan, and P. Boomi, “In vitro antibacterial activity of the metal oxide nanoparticles against urinary tract infectious bacterial pathogens”, Asian Pacific Journal of Tropical Disease, Vol. 2, No.2, pp.85–89, 2012.
  18. Pellieux, A. Dewilde, C. Pierlot, and J-M. Aubry, “Bactericidal and virucidal activities of singlet oxygen generated by thermolys is of naphthalene endoperoxides”, Methods in Enzymology, Vol. 319, pp.197–207, 2000.
  19. Eddie, Chang, S. Christa, and D. Andrew Knight, “Cobalt Complexes as Antiviral and Antibacterial Agents”, Pharmaceuticals (Basel), Vol. 3, pp. 1711–1728, 2010.
  20. L. Kalyani, J. Venkatraju, P. Kollu, N. H. Rao, and S. V. N. Pammi, “Low temperature synthesis of various transition metal oxides and their antibacterial activity against multidrug resistance bacterial pathogens”, Korean Journal of Chemical Engineering, Vol. 32, No.5, pp. 911-6, 2015.
  21. S. Kim, E. Kuk, K. N. Yu, J. H. Kim, S. J. Park, H. J. Lee, S. H. Kim, Y. K. Park, Y.H. Park, C.Y. Hwang, Y. K. Kim, Y. S. Lee, D. H. Jeong, and M. H. Cho, “Antimicrobial effects of silver nanoparticles”, Nanomedicine, Vol. 3, pp. 95–101, 2007.
  22. Sondi, and B. Salopek-Sondi, “Silver nanoparticles as antimicrobial agent: a case study on E. coli as a model for Gram-negative bacteria”, Journal of Colloid and Interface Science, Vol. 275, pp. 177–182, 2004.
  23. F. Deravi, J. D. Swartz, and D. W. Wright, “The biomimetic synthesis of metal oxide nanomaterials”, Wiley; 2010.
  24. Mu, J. Tang, Q. Liu, C. Sun, T. Wang, and J. Duan, “Potent antibacterial nanoparticles against biofilm and intracellular bacteria”, Scientific Reports, Vol. 6, pp. 18877, 2016.
  25. H-Z. Lai, W-Y. Chen, C-Y. Wu, and Y-C. Chen, “Potent antibacterial nanoparticles for athogenic bacteria”, ACS Applied Materials and Interfaces, 7, pp. 2046–54, 2015.

AJSAT is covering all aspects of Science and Applied Technology areas. Topics include, but are not limited to:

Chemistry
Physics
Astronomy
Earth Science
Environmental Science
Biology
Computer Science
Mathematics
Statistics
Systems Science

The indiscriminate usage of antibiotics in the past few years is one of the main reasons behind increased incidences of antimicrobial resistance. The development of potent antibacterial agents to combat this problem is the need of present era. In view of this, in present study, cobalt (Co) nanoparticles were chemically synthesized by standard method. The synthesized Co nanoparticles were tested against the S. aureus and E. coli bacterial strains, and the minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations (MBC) values of Co nanoparticles were determined against these bacterial strains on the day of Co nanoparticles synthesis and after their storage for 30 and 60 days. The Co nanoparticles showed antibacterial actions against S. aureus and E. coli bacterial strains. The MIC values of fresh chemically synthesized Co nanoparticles in this study for S. aureus and E. coli were 140.0 μg/ml and 100.0 μg/ml, respectively. The MBC values of these nanoparticles for S. aureus and E. coli were 260.0 μg/ml and 220.0 μg/ml, respectively. The MIC and MBC values of Co nanoparticles increased on storage of its suspensions for 30 as well as 60 days. It might be considered as potent antibacterial candidate in future after some additional investigations.

Editor-in-Chief
Dr. Balaji Ramachandran
Department of Applied Sciences, Nicholls State University, Louisiana, United States
[email protected]
Editorial Advisory Board
Dr. Maamar Benkraouda
Department of Physics, United Arab Emirates University, UAE
[email protected]
Dr. Rasheed Al Hammadi
Department of Biology, United Arab Emirates University, UAE
[email protected]
Dr. Dimitrios P. Nikolelis
Department of Chemistry, University of Athens, Greece
[email protected]
Dr. Fauziah Binti Shahul Hamid
Institute of Biological Sciences, University of Malaya, Malaysia
[email protected]
Dr. Karni S Moshal
Department of Medicine, Alpert Medical School of Brown University, USA
[email protected]
Dr. Koh You Beng
Institute of Mathematical Sciences, University of Malaya, Malaysia
[email protected]
Dr. Lim Sok Li
Institute of Mathematical Sciences, University of Malaya, Malaysia
[email protected]
Dr. Ramesh Kasi
Department of Physics, University of Malaya, Malaysia
[email protected]
Dr. Jasmine Elanie Binti Khairat
Institute of Biological Sciences, University of Malaya, Malaysia
[email protected]
Dr. Nur Airina Binti Muhamad
Institute of Biological Sciences, University of Malaya, Malaysia
[email protected]
Dr. Amizah Malip
Department of Applied Mathematics, University of Malaya, Malaysia
[email protected]
Dr. Azzuliani Binti Supangat
Department of Physics, University of Malaya, Malaysia
[email protected]
Prof. Mohamed Toutounji
Professor, Department of Chemistry, United Arab Emirates University, UAE
[email protected]
Dr. Mohd Azmi Haron
Institute of Mathematical Sciences, University of Malaya, Malaysia
[email protected]
Prof. Noordini Mohamad Salleh
Department of Chemistry, University of Malaya, Malaysia
[email protected]
Dr. Ibrahim Bin Mohamed
Institute of Mathematical Sciences, University of Malaya, Malaysia
[email protected]
Dr. Halijah Ibrahim
Institute of Biological Sciences, University of Malaya, Malaysia
[email protected]
Dr. S. Chandra Kishore
Assistant Professor, University of Information Science and Technology,
“St. Paul The Apostle”, Macedonia, Greece
[email protected]
Dr. Salah Nasri
Department of Physics, United Arab Emirates University, UAE
[email protected]
Dr. Dharini Pathmanathan
Institute of Mathematical Sciences, University of Malaya, Malaysia
[email protected]

2016

2015

2014

  • Results
  • Asian Review of Mechanical Engineering (ARME)
  • career

2013

  • Home
  • Shop
  • My Account
  • Logout
  • Contact us
  • The Asian Review of Civil Engineering (TARCE)

2012

  • Asian Journal of Electrical Sciences(AJES)
  • Asian Journal of Information Science and Technology (AJIST)
  • Asian Journal of Engineering and Applied Technology (AJEAT)
  • Asian Journal of Science and Applied Technology (AJSAT)
  • Asian Journal of Managerial Science (AJMS)
  • Asian Review of Social Sciences (ARSS)

2011

2010

    Table of Contents

    Editorial Note

    Editorial Dr. Balaji Ramachandran

    Editor-in-Chief
    Dr. Balaji Ramachandran
    Department of Applied Sciences, Nicholls State University, Louisiana, United States
    [email protected]
    Editorial Advisory Board
    Dr. Maamar Benkraouda
    Department of Physics, United Arab Emirates University, UAE
    [email protected]
    Dr. Rasheed Al Hammadi
    Department of Biology, United Arab Emirates University, UAE
    [email protected]
    Dr. Dimitrios P. Nikolelis
    Department of Chemistry, University of Athens, Greece
    [email protected]
    Dr. Fauziah Binti Shahul Hamid
    Institute of Biological Sciences, University of Malaya, Malaysia
    [email protected]
    Dr. Karni S Moshal
    Department of Medicine, Alpert Medical School of Brown University, USA
    [email protected]
    Dr. Koh You Beng
    Institute of Mathematical Sciences, University of Malaya, Malaysia
    [email protected]
    Dr. Lim Sok Li
    Institute of Mathematical Sciences, University of Malaya, Malaysia
    [email protected]
    Dr. Ramesh Kasi
    Department of Physics, University of Malaya, Malaysia
    [email protected]
    Dr. Jasmine Elanie Binti Khairat
    Institute of Biological Sciences, University of Malaya, Malaysia
    [email protected]
    Dr. Nur Airina Binti Muhamad
    Institute of Biological Sciences, University of Malaya, Malaysia
    [email protected]
    Dr. Amizah Malip
    Department of Applied Mathematics, University of Malaya, Malaysia
    [email protected]
    Dr. Azzuliani Binti Supangat
    Department of Physics, University of Malaya, Malaysia
    [email protected]
    Prof. Mohamed Toutounji
    Professor, Department of Chemistry, United Arab Emirates University, UAE
    [email protected]
    Dr. Mohd Azmi Haron
    Institute of Mathematical Sciences, University of Malaya, Malaysia
    [email protected]
    Prof. Noordini Mohamad Salleh
    Department of Chemistry, University of Malaya, Malaysia
    [email protected]
    Dr. Ibrahim Bin Mohamed
    Institute of Mathematical Sciences, University of Malaya, Malaysia
    [email protected]
    Dr. Halijah Ibrahim
    Institute of Biological Sciences, University of Malaya, Malaysia
    [email protected]
    Dr. S. Chandra Kishore
    Assistant Professor, University of Information Science and Technology,
    “St. Paul The Apostle”, Macedonia, Greece
    [email protected]
    Dr. Salah Nasri
    Department of Physics, United Arab Emirates University, UAE
    [email protected]
    Dr. Dharini Pathmanathan
    Institute of Mathematical Sciences, University of Malaya, Malaysia
    [email protected]

    Articles

Advanced Search

You can submit your research paper to the journal in just a few clicks. Please follow the steps outlined below: 1. Register your details and select to be an Author 2. Log in with your user name and password 3. ‘Start a new submission’ and follow these 5 steps:

[gravityform id="1" name="Registration" title="false" description="false"]

Privacy Statement

The names and email addresses entered in this journal site will be used exclusively for the stated purposes of this journal and will not be made available for any other purpose or to any other party.

Privacy Statement

The names and email addresses entered in this journal site will be used exclusively for the stated purposes of this journal and will not be made available for any other purpose or to any other party.

Lorem1 ipsum dolor sit amet, consectetur adipiscing elit. Nulla convallis ultricies scelerisque. Fusce dolor augue, sollicitudin eget lacus vitae, rutrum commodo lacus. Praesent ullamcorper facilisis dui. Sed suscipit id lorem ut dapibus. Integer dictum cursus nisl, quis ullamcorper augue. Sed non rutrum mauris. Maecenas in dolor est. Donec eget sagittis mi. Sed non leo eu odio mollis pulvinar vitae et leo. Integer eu feugiat tortor. Duis massa purus, eleifend id erat eget, hendrerit semper risus. Suspendisse cursus varius dapibus

Lorem1 ipsum dolor sit amet, consectetur adipiscing elit. Nulla convallis ultricies scelerisque. Fusce dolor augue, sollicitudin eget lacus vitae, rutrum commodo lacus. Praesent ullamcorper facilisis dui. Sed suscipit id lorem ut dapibus. Integer dictum cursus nisl, quis ullamcorper augue.

Subscription

Subscription (for 12 issues):
Rs. 5000; Overseas - USD 500;
Cheque drawn in favour of "Informatics Publishing Limited"
Click here to download online subscription form

Download

DD Mailing Address

Lorem1 ipsum dolor sit amet,
Lorem1 ipsum dolor sit amet,
Lorem1 ipsum dolor sit amet.

BACK TO TOP

Outstanding Scholars

The Journals honor Outstanding Scholars in various fields. Scholar of the Month should have contributed to their field and to the larger community. Recipients will be nominated by the Advisory Board and approved by the Editor-in-Chief of the allied journals published by The Research Publication. Scholar of the Month will be displayed in the web portal of the concerned journal.

Please send your brief write up to [email protected]

Editors and Reviewers

The Research Publication is seeking qualified researchers to join its editorial team as Associate Editor, Editorial Advisory Board Member, and Reviewers.
Kindly send your details to [email protected]

Call For Papers

Authors are requested to submit their papers electronically to [email protected] with mentioning the journal title.

Mailing Address

The Research Publication 1/611, Maruthi Nagar, Rakkipalayam Post, Coimbatore – 641 031, Tamil Nadu, India Phone No.: 0422 2461001

  • About
  • Editorial Policy
  • Author Guidelines
  • Contact us
  • Copyright
  • Facebook
  • Twitter
  • RSS

© 2015 The Research Publication. All rights reserved.

The Research Publication
  • Home
  • Editorial Policy
  • Author Guidelines
  • Submission
  • Copyright Form
  • Career
  • Contact us
  • Subscription